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更新时间:   2014-12-26

广州Atrasentan(ABT-627)III期临床试验-Atrasentan的糖尿病肾病研究

广州南方医科大学南方医院开展的Atrasentan(ABT-627)III期临床试验信息,需要患者受试者,主要适应症为糖尿病肾病
  上一个试验     目前是第 13634 个试验/共 18798 个试验     下一个试验  
登记号 CTR20140661 试验状态 主动暂停
申请人联系人 康越 首次公示信息日期 2014-12-26
申请人名称 AbbVie Inc./ AbbVie Ireland NL B.V./ 艾伯维医药贸易(上海)有限公司
一、题目和背景信息
登记号 CTR20140661
相关登记号 暂无
药物名称 Atrasentan (ABT-627)
药物类型 化学药物
临床申请受理号 企业选择不公示
适应症 糖尿病肾病
试验专业题目 评价Atrasentan对Ⅱ型糖尿病肾病受试者肾脏预后影响的随机多国家多中心双盲平行安慰剂对照研究 SONAR:Atrasentan的糖尿病肾病研究
试验通俗题目 Atrasentan的糖尿病肾病研究
试验方案编号 M11-352 方案最新版本号 暂无
版本日期: 暂无 方案是否为联合用药 企业选择不公示
二、申请人信息
申请人名称
1
2
3
联系人姓名 康越 联系人座机 021-62631384 联系人手机号 暂无
联系人Email yue.kang@abbvie.com 联系人邮政地址 上海市南京西路288号创兴金融中心17楼 联系人邮编 200003
三、临床试验信息
1、试验目的
评价与安慰剂相比, Atrasentan对2型糖尿病肾病受试者血清肌酐倍增所需时间或终末期肾病(ESRD)出现时间的影响。此外,本研究评估与安慰剂相比, Atrasentan对下述结果的影响:心血管发病率和死亡率、尿白蛋白排泄率、估算的肾小球滤过率变化,还评估对Ⅱ型糖尿病肾病受试者生活质量的影响。
2、试验设计
试验分类 安全性和有效性 试验分期 III期 设计类型 平行分组
随机化 随机化 盲法 双盲 试验范围 国际多中心试验
3、受试者信息
年龄 18岁(最小年龄)至 85岁(最大年龄)
性别 男+女
健康受试者
入选标准
1 受试者身患Ⅱ型糖尿病,在筛选期之前3个月内,至少接受一种降糖药物和ACEi/或ARB(RAS抑制剂)治疗。受试者不能为Ⅰ型糖尿病患者(定义为:在35岁之前发病,并在1型糖尿病确诊后12月内需要长期胰岛素治疗)。
2 HbA1c ≤ 12%
3 为了进入准备期,根据实验室筛选指标,受试者必须满足下述标准:估算的GFR为25~75mL/min/1.73m2,UACR≥300、3.0(3 mmol/L)、≤5.5 mEq/L(5.5 mmol/L);
4 为了进入强化期,根据准备期最后一次访视结果,受试者必须满足下述标准:接受RAS抑制剂MTLDD剂量已治疗4周,且未调整过剂量;在筛选时,接受RAS抑制剂MTLDD剂量治疗、但未接受利尿剂治疗(除非有医疗禁忌症)的受试者必须进入至少两周的准备期。
5 为了进入双盲治疗期,根据强化期最后一次访视结果,受试者必须满足下述标准:在强化期内,已接受RAS抑制剂MTLDD剂量治疗过6周,且未曾调整过剂量;接受任一剂量利尿剂,除非经研究者判断有医疗禁忌症或临床不能耐受(即:低血压或低钾血症);从强化期开始的6周强化期间,体重变化
排除标准
1 在筛选前6个月内,有中度或重度外周水肿、与外伤无关的肺水肿或面部水肿等病史的受试者,或有粘液性水肿病史的受试者;
2 有肺动脉高血压病史且需要输氧治疗和/或内皮素受体拮抗剂或磷酸二酯酶治疗的受试者;或有任一种肺病(比如:慢性阻塞性肺病、肺气肿、肺纤维化)且需要输氧治疗的受试者;
3 受试者已有记录诊断为心衰,或因心衰或与心衰相符的症状(运动性呼吸困难、脚肿、端坐呼吸、发作性夜间呼吸困难;其他原因未能解释这些症状)而住院,且治疗心衰的药物或其他治疗措施有变化。
4 已知受试者罹患非糖尿病肾病(肾结石除外);
5 在过去6个月内,受试者有症状性低血压病史;
4、试验分组
试验药
序号 名称 用法
1 中文通用名:Atrasentan(ABT-627)
用法用量:薄膜衣片;规格0.75mg;口服,一日一次,48个月。
对照药
序号 名称 用法
1 中文通用名:安慰剂
用法用量:薄膜衣片;口服,一日一次,48个月。
5、终点指标
主要终点指标及评价时间
序号 指标 评价时间 终点指标选择
1 首次出现肾脏复合终点所需时间:血清肌酐倍增(30天血清肌酐确认)或ESRD发病(需要长期透析或肾移植或肾死亡)。 大约48个月 有效性指标+安全性指标
次要终点指标及评价时间
序号 指标 评价时间 终点指标选择
1 UACR从基线至随机分组第24个月访视时的变化; 从第0天至第24个月 有效性指标+安全性指标
2 从随机分组起治疗3个月后,eGFR下降30%所需时间; 大约24个月 有效性指标+安全性指标
3 出现心肾复合终点所需时间:血清肌酐倍增、ESRD、CV死亡、非致命性心肌梗死、非致命性卒中; 大约48个月 有效性指标+安全性指标
4 出现CV复合终点所需时间:CV死亡、非致命性心肌梗死和非致命性卒中; 大约48个月 有效性指标+安全性指标
四、研究者信息
1、主要研究者信息
1 姓名 侯凡凡 学位 暂无 职称 教授,主任医师,中国科学院院士
电话 020-61641591 Email ffhouguangzhou@163.com 邮政地址 广东省广州市广州大道北1838号
邮编 510515 单位名称 南方医科大学南方医院
2、各参加机构信息
序号 机构名称 主要研究者 国家 省(州) 城市
1 南方医科大学南方医院 侯凡凡 中国 广东省 广州
2 广东省人民医院 史伟 中国 广东省 广州
3 复旦大学附属华山医院 郝传明 中国 上海 上海
4 北京大学人民医院 左力 中国 北京 北京
5 北京大学人民医院 纪立农 中国 北京 北京
6 北京协和医院 李玉秀 中国 北京 北京
7 北京大学第一医院 郭晓蕙 中国 北京 北京
8 北京大学第三医院 王松 中国 北京 北京
9 上海交通大学医学院附属仁济医院 倪兆慧 中国 上海 上海
10 武汉大学人民医院 丁国华 中国 湖北省 武汉
11 上海交通大学医学院附属瑞金医院 陈楠 中国 上海 上海
12 山东省立医院 赵家军 中国 山东省 济南
13 青岛大学附属医院 徐岩 中国 山东省 青岛
14 第四军医大学第一附属医院(西京医院) 姬秋和 中国 陕西省 西安
15 第四军医大学第一附属医院(西京医院) 孙世仁 中国 陕西省 西安
16 中国人民解放军第三军医大学第一附属医院 吴雄飞 中国 重庆 重庆
17 南京医科大学第一附属医院 邢昌赢 中国 江苏省 南京
18 西安交通大学第一附属医院 施秉银 中国 陕西省 西安
19 佛山市第一人民医院 肖观清 中国 广东省 佛山
20 华中科技大学同济医学院附属同济医院 徐钢 中国 湖北省 武汉
21 四川大学华西医院 付平 中国 四川省 成都
22 东南大学附属中大医院 刘必成 中国 江苏省 南京
23 复旦大学附属中山医院 丁小强 中国 上海 上海
24 上海市第六人民医院 贾伟平 中国 上海 上海
25 首都医科大学附属北京同仁医院 杨金奎 中国 北京 北京
26 大连医科大学附属第二医院 苏本利 中国 辽宁省 大连
27 中山大学附属第三医院 翁建平 中国 广东省 广州
28 北京大学第一医院 赵明辉 中国 北京 北京
29 上海长征医院 郁胜强 中国 上海 上海
30 Apex Medical Research, Inc. Ahmed Azazuddin United States Illinois Chicago
31 Farmington Research LLC Amin Mohammad United States Missouri Farmington
32 Biolab Research, LLC Belledonne Mario United States MARYLAND Rockville
33 California Institute of Renal Research Belo Diogo United States CALIFORNIA Chula Vista
34 Academic Medical Research Institute El-Shahawy Mohamed United States California Los Angeles
35 California Institute of Renal Research Fadda George United States California La Mesa
36 East West Medical Research Institute Fitz-Patrick David United States Hawaii Honolulu
37 Brookview Hills Research Associates, LLC Greenwood Gregory United States North Carolina Winston-Salem
38 Hypertension and Renal Research Group Herman Theodore United States New York Orchard Park
39 North Shore Diabetes and Endocrine Associates Hershon Kenneth United States NEW YORK New Hyde Park
40 North America Research Institute Jamal Aamir United States CALIFORNIA Azusa
41 Metabolic Research Institute, Inc. Kaye William United States FLORIDA West Palm Beach
42 Northeast Clinical Research Centers, LLC Kopyt Nelson United States Pennsylvania Bethlehem
43 South Texas Kidney Specialists, PA Mangoo-Karim Roberto United States Texas McAllen
44 Model Clinical Research Mersey James United States MARYLAND Baltimore
45 Hurley Medical Center Osama Sayed United States Michigan Flint
46 Clinical Advancement Center, PLLC Pergola Pablo United States Texas San Antonio
47 Creighton University Medical Center Rendell Marc United States Nebraska Omaha
48 Tulane University Health Sciences Center Simon Eric United States Louisiana New Orleans
49 Pines Clinical Research, Inc. Zeig Steven United States Florida Pembroke Pines
50 Metrolina Nephrology Associates, PA Chuang Peale United States North Carolina Charlotte
51 Sansum Clinic Elder John United States California Santa Barbara
52 Desert Medical Group, Inc. Jardula Michael United States California Palm Springs
53 Texas Tech University Health Sciences Center Ahmed Vaqar United States Texas Lubbock
54 George Washington University Medical Faculty Associates Cohen Scott United States District of Columbia Washington
55 MetroHealth Medical Center Sedor John United States Ohio Cleveland
56 Rhode Island Hospital Bayliss George United States Rhode Island Providence
57 Axis Clinical Trials Hazan Lydie United States California Los Angeles
58 FPA Family Health Care Clinical Studies Link Michael United States FLORIDA Kissimmee
59 Down East Medical Associates, P.A. Lawrence Mary United States North Carolina Morehead
60 University of Cincinnati, College of Medicine El-Khatib Mahmoud United States Ohio Cincinnati
61 Gwinnett Biomedical Research Lalwani Tarik United States Georgia Lawrenceville
62 San Diego Coastal Endocrinology Group, aMC Argoud Georges United States California Chula Vista
63 PrimeCare Medical Group Doshi Ankur United States Texas Houston
64 Green Clinic LLC Nammour Michael United States Louisiana Ruston
65 Eastern Nephrology Associates, PLCC Montero Manuel United States North Carolina New Bern
66 St. Jude Hospital Gilbert John United States California Fullerton
67 University of Chicago Bakris George United States Illinois Chicago
68 Emory University Hospital Guasch Antonio United States Atlanta Georgia
69 Providence Clinical Research Sligh Teresa United States North Hollywood California
70 University of Tennessee Health Sciences Center Kovesdy Csaba United States Memphis Tennessee
71 Hypertension and Nephrology Associates PA Liss Kenneth United States Eatontown New Jersey
72 Endocrinology Associates, Inc. Christofides Elena United States Columbus Ohio
73 Louisiana State University Health Sciences Center Reisin Efrain United States New Orleans Louisiana
74 Clinical Research Development Associates, LLC Scott David United States Rosedale New York
75 University of Mississippi Medical Center Juncos Luis United States Jackson Mississippi
76 Capital Nephrology Medical Group Atray Naveen United States Sacramento California
77 East Carolina University Nephrology Research Hames Melanie United States Greenville North Carolina
78 Boice-Willis Clinic, P.A. Jere Charles United States Rocky Mount North Carolina
79 My Kidney Center, LLC Bedros Fadi United States Manhattan Kansas
80 Jersey Shore University Medical Center Asnani Sunil United States Neptune New Jersey
81 Sierra Nevada Nephrology Consultants Vicks Steven United States Reno Nevada
82 Stamford Nephrology Brown Eric United States Connecticut Stamford
83 Briggs Clinical Research, LLC Gaona, Sr. Raul United States Texas San Antonio
84 National Research Institute Frias Juan United States California Los Angeles
85 Cooper Nephrology McFadden Christopher United States New Jersey Camden
86 Herman Clinical Research, LLC Herman Lee United States Georgia Suwanee
87 Columbia Nephrology Associates, PA Buerkert John United States South Carolina Columbia
88 Apex Medical Research, MI,Inc. Arif Ahmed United States Michigan Flint
89 Alta Pharmaceutical Research Center, Inc. Miller Alan United States GEORGIA Dunwoody
90 University of Utah Beddhu Srinivasan United States Utah Salt Lake City
91 Central Florida Internists Khan Muhammad United States Florida St. Cloud
92 Remedica LLC Tatu Horia United States Michigan Rochester
93 Lucita M. Cruz MD Cruz Lucita United States California Norwalk
94 Knoxville Kidney Center, PLLC Newman George United States Tennessee Knoxville
95 West Virginia University, School of Medicine Schmidt Rebecca United States West Virginia Morgantown
96 Nephrology Associates of Northern Virginia, Inc. Assefi Ali United States VIRGINIA Fairfax
97 Kaufman, New York, NY Kaufman Allen United States New York New York
98 Lee County Internal Medicine Associates Bohm Guillermo United States Florida Fort Myers
99 California Institute of Renal Research Boiskin Mark United States CALIFORNIA San Diego
100 Nephrology Associates P.C. Brantley Roman United States Alabama Birmingham
101 Houston Nephrology Group Chatha Rupi United States Texas Houston
102 Hanson Clinical Research Center Hanson Lenita United States Florida Port Charlotte
103 South Florida Nephrology Group, PA Jacob Radu United States Florida Coral Springs
104 Seacoast Kidney and Hypertension Specialists, PLLC Joshi Sucharit United States New Hampshire Portsmouth
105 Oregon Health and Science University Rueda Jose United States Oregon Portland
106 Palm Research Center, Inc. Nakhle Samer United States Nevada Las Vegas
107 Preferred Primary Care Physicians, Inc Purighalla Raman United States Pennsylvania Pittsburgh
108 Anne Arundel Medical Center (AAMC) Welker James United States Maryland Annapolis
109 Diagnostic Clinic Of Houston Varghese Freemu United States Texas Houston
110 University of Louisville Jacobs Alfred United States Kentucky Louisville
111 Texas Health Physicians Group Arauz-Pacheco Carlos United States Texas Dallas
112 Thomas Jefferson University Hospital Jabbour Serge United States Pennsylvania Philadelphia
113 Renal Medicine Associates Kumar Jayant United States New Mexico Albuquerque
114 NYU Langone Medical Center Wissner-Greene Loren United States New York New York
115 East Texas Nephrology Associates Nazeer Imran United States Texas Lufkin
116 Rogosin Institute Perlman Alan United States New York New York
117 Drexel University College of Medicine Ahmed Ziauddin United States Pennsylvania Philadelphia
118 Arizona Kidney Disease and Hypertension Center Desai Sachin United States Arizona Phoneix
119 Carolina Health Specialists Eagerton Donald United States South Carolina Myrtle Beach
120 Penn State, Milton S. Hershey Medical Center Farooq Umar United States Pennsylvania Hershey
121 Diabetes Associates Medical Group Madu Ivy-Joan United States California Orange
122 Fletcher Allen Health Care, Burlington, Vermont Solomon Richard United States Vermont Burlington
123 APEX Research of Riverside Lee Joseph United States CALIFORNIA Riverside
124 Univ of Texas Health Science Center at San Antonio Bansal Shweta United States Texas San Antonio
125 University of New Mexico Adolphe Allen United States New Mexico Albuquerque
126 University of Iowa Dixon Brad United States Iowa Iowa City
127 Temple University Hospital Benjamin Joseph United States Pennsylvania Philadelphia
128 North Texas Endocrine Center Bressler Peter United States Texas Dallas
129 Northside Internal Medicine DEXA Cathcart Harold United States Washington Spokane
130 Kaiser Foundation Health Plan of Georgia, Inc. Muoneke Rosemary United States Georgia Duluth
131 Atlanta Nephrology Referral Center Sharon Zeev United States Georgia Decatur
132 San Antonio Kidney Disease Center Physicians Group, PLLC Gouge Steven United States Texas San Antonio
133 Ladan Golestaneh, MD, MS Golestaneh Laden United States New York Bronx
134 Maine Research Associates Weiss Robert United States Maine Auburn
135 Mohammed Ismail, MD, Inc. Ismail Mohammad United States California Paramount
136 Four Rivers Clinical Research, Inc. De La Rosa, Raymond United States Kentucky Paducah
137 Internal Medicine Specialists Rodriguez-Araya Eduardo United States Louisiana New Orleans
138 Community Clinical Research Center Bakdash Wa'el United States Indiana Anderson
139 Independent Clinical Research Butt Salman United States Texas McKinney
140 Yale Univ School of Medicine Dahl Neera United States Connecticut New Haven
141 San Marcus Research Clinic, Inc. Acosta Idalia United States Florida Miami
142 Compass Research, LLC Stoica George United States Florida Orlando
143 Texas Renal Care Ijaz Adeel United States TEXAS Greenville
144 Pines Care Research Center, Inc. Moya Hechevarria Jaynier United States Florida Pembroke Pines
145 Cleveland Clinic Foundation Taliercio John United States Ohio Cleveland
146 Ochsner Clinic Foundation Reichel Ronald United States Louisiana New Orleans
147 NY Clinical Trials Bloom Scott United States New York New York
148 Erie County Medical Center Gundroo Aijaz United States New York Buffalo
149 Angiocardiac Care of Texas, PA Karim Amin United States Texas Houston
150 SUNY Downstate Medical Center Markell Mariana United States New York Brooklyn
151 Sensenbrenner Primary Care, Charlotte, NC Sensenbrenner John United States NORTH CAROLINA Charlotte
152 Pentucket Medical Associates, LLC Dulude Emily United States Massachusetts Haverhill
153 Crescent City Clinical Research Center, LLC Wise Jonathan United States Louisiana Metairie
154 Diagnostic Clinic Of Houston Tulloch Brian United States Texas Houston
155 National Institute of Clinical Research Joshi Sudhir United States California Bakersfield
156 Kidney Innovations Levine Andrew United States Texas Weslaco
157 Renaissance Renal Research Institute, LLC Khairullah Quresh United States Michigan Detroit
158 Kidney Care Center Awua-Larbi Stella United States Illinois Joliet
159 Kidney and Hypertension Care Center Khan Mehreen United States Texas Houston
160 Meridien Research Group Chaykin Louis United States Florida Bradenton
161 Premier Research Associate, Inc De la Calle Gilda United States Florida Hialeah
162 Nephrology Associates Research Center Minga Todd United States Florida Panama City
163 NorthShore University HealthSystem Sarav Menaka United States Illinois Evanston
164 Innovative Medical Research of South Florida, Inc. Schlessinger Fabiola United States Florida Aventura
165 University of Florida Hall Karen United States Florida Gainesville
166 Southern Utah Kidney and Hypertension Center Leon-Forero Carlos United States Utah Saint George
167 AKDHC Medical Research Services, LLC Nica Romanita United States Arizona Prescott
168 California Renal Research Network, LLC Minasian Raffi United States California Glendale
169 Professional Health Care of Pinellas Saba Fadi United States Florida St. Petersburg
170 Clinical Research of Brandon, LLC Alvarez German United States Florida Brandon
171 Audie L. Murphy VA Hospital, STVHCS Fanti Paolo United States Texas San Antonio
172 Pentucket Medical Associates, LLC Tarkan Joshua United States Massachusetts Newburyport
173 VAMC Cincinnati Thakar Charuhas United States Ohio Cincinnati
174 Emory University and Atlanta VA Medical Center Phillips Lawrence United States Georgia Decatur
175 Zablocki VA Medical Center Blumenthal Samuel United States Wisconsin Milwaukee
176 VA Long Beach Healthcare System Levin Ellis United States CALIFORNIA Long Beach
177 CEREHA Elbert Alicia Argentina Avellaneda Avellaneda
178 Instituto de Investigaciones Clinicas Bahia Blanca Vogel Daniel Argentina Buenos Aires Buenos Aires
179 Instituto de Investigaciones Medicas Alfredo Lanari Zucchini Alfredo Argentina Buenos Aires Buenos Aires
180 Consultorios Asociados de Endocrinologia / Inv Clin Aplicado Maffei Laura Argentina Buenos Aires Buenos Aires
181 Hospital Italiano de Buenos Aires Greloni Gustavo Argentina Buenos Aires Buenos Aires
182 CEMIC (Centro Educacion Medica e Investigacion Clinica) Diaz Carlos Argentina Buenos Aires Buenos Aires
183 Instituto Latinoamericano de Investigaciones Medicas Ulla Maria Argentina Cordoba Cordoba
184 Fundacion J. Robert Cade Juncos Luis Argentina Cordoba Cordoba
185 Blossom DMO Garcia Nestor Argentina Cordoba Cordoba
186 Instituto Cardiologia de Corrientes Juana Francisca Cabral Farias Eduardo Argentina Corrientes Corrientes
187 Centro de Salud Renal Junin S.R.L. Vallejos Augusto Argentina Junin Junin
188 Instituto de Nefrologia Pergamino S.R.L. Cusumano Ana Argentina Pergamino Pergamino
189 Investigaciones Clinicas Tucuman Santos Juan Argentina San Miguel de Tucuman San Miguel de Tucuman
190 Royal Prince Alfred Hospital Chadban Steve Australia New South Wales Camperdown
191 Renal Research Roger Simon Australia New South Wales Gosford
192 Liverpool Hospital Suranyi Michael Australia New South Wales Liverpool
193 The Prince of Wales Hospital Endre Zoltan Australia New South Wales Randwick
194 Royal North Shore Hospital Pollock Carol Australia New South Wales St Leonards
195 Nambour General Hospital Gray Nicholas Australia Queensland Nambour
196 Southern Adelaide Diabetes Endocrine Services Stranks Stephen Australia South Australia Daw Park
197 Royal Melbourne Hospital Toussaint Nigel Australia Victoria Parkville
198 Fremantle Hospital Davis Tim Australia Western Australia Fremantle
199 Sir Charles Gairdner Hospital Chan Doris Australia Western Australia Nedlands
200 Box Hill Hospital Fraenkel Margaret Australia Box Hill Box Hill
201 Concord Repatriation and General Hospital Gallagher Martin Australia Concord Concord
202 Launceston General Hospital Cooke Duncan Australia Launceston Launceston
203 John Hunter Hospital Acharya Shamasunder Australia New Lambton New Lambton
204 St. Vincents Hospital Melbourne MacIsaac Richard Australia Victoria Victoria
205 CHR de la Citadelle Warling Xavier Belgium Liege Liege
206 Cliniques Universitaires Saint Luc Jadoul Michel Belgium Brussels Brussels
207 Onze Lieve Vrouw Hospital Van Vlem Bruno Belgium Aalst Aalst
208 Universitair Ziekenhuis Leuven Gillard Pieter Belgium Leuven Leuven
209 Centro de Estudos em Diabetes e Hipertensao Forti Adriana Costa Brazil Ceara Fortaleza
210 Hospital Geral de Goiania Rassi Nelson Brazil Goias Goiania
211 Hospital Sao Lucas-PUCRS D'Avila Domingos Brazil Rio Grande do Sul Porto Alegre
212 Irmandade da Santa Casa de Misericordia de Porto Alegre Keitel Elizete Brazil Rio Grande do Sul Porto Alegre
213 Clinica de Endocrinologia Fraige Filho Fadlo Brazil Sao Paulo Sao Paulo
214 University Federal de Sao Paulo Chacra Antonio Brazil Sao Paulo Sao Paulo
215 IPEC - Instituto de Pesquisa Clinica Salles, Joao Eduardo Brazil Sao Paulo Sao Paulo
216 Instituto Dante Pazzanese de Cardiologia Amodeo Celso Brazil Sao Paulo Sao Paulo
217 The Bailey Clinic Bailey Gordon Canada Alberta Red Deer
218 St. Paul's Hospital Levin Adeera Canada British Columbia Vancouver
219 Clinical Research Solutions Inc. Jolly Shivinder Canada Ontario Kitchener
220 OTT Healthcare Inc. Tam Paul Canada Ontario Scarborough
221 Toronto East General Medical Centre Chow Stephen Canada Ontario East York
222 LMC Diabetes and Endocrinology Bajaj Harpeet Canada Ontario Brampton
223 LMC Diabetes and Endocrinology Khandwala Hasnain Canada Ontario Etobicoke
224 LMC Diabetes and Endocrinology Aronson Ronnie Canada Ontario Toronto
225 Co-Medica Research Network, Inc Steele Andrew Canada Ontario Courtice
226 Humber River Regional Hospital Nesrallah Gihad Canada Ontario Toronto
227 JBN Medical Diagnostic Services Inc. Berlingieri Joseph Canada Ontario Burlington
228 St. Joseph's Healthcare Rabbat Christian Canada Ontario Hamilton
229 Medicor Research Inc. Goluch Richard Canada Ontario Sudbury
230 Centre de Sante et de Services Sociaux Champlain Cournoyer Serge Canada Quebec Greenfield Park
231 Hospital Maisonneuve-Rosemont Pichette Vincent Canada Quebec Montreal
232 CHUM - Hopital Saint-Luc Roy Louise Canada Quebec Montreal
233 CALMED Castillo Alvaro Chile La Serena La Serena
234 Servicios Medicos Godoy Limitada Godoy Gonzalo Chile Santiago Santiago
235 Biomedica Research Group Gutierrez Vicente Chile Santiago Santiago
236 Hospital Clinico Regional Dr. Guillermo Grant Benavente Munoz Rodrigo Chile Concepcion Concepcion
237 Hospital del Salvador Gonzalez Fernando Chile Providencia, Santiago Providencia, Santiago
238 Petr Bucek s.r.o. Bucek Petr Czech Republic Frydek-Mistek Frydek-Mistek
239 Masarykova mestska nemocnice Oplustilova Alexandra Czech Republic Jilemnice Jilemnice
240 Fakultni Nemocnice Ostrava Valkovsky Ivo Czech Republic Ostrava-Poruba Ostrava-Poruba
241 Diabetologicka ambulance Pavlickova Jirina Czech Republic Pardubice Pardubice
242 PeMedica.CZ, s.r.o. Petr Martin Czech Republic Prague Prague
243 Vseobecna fakultni nemocnice v Praze (VFN) Tesar Vladimir Czech Republic Prague Prague
244 Fakultni Nemocnice Kralovske Vinohrady FNKV Rychlik Ivan Czech Republic Prague 10 Prague 10
245 Milan Kvapil s.r.o. Bartaskova Dagmar Czech Republic Prague 4 Prague 4
246 Nemocnice Trebic Chmelickova Hana Czech Republic Trebic Trebic
247 Slagelse Hospital Gaede Peter Denmark Slagelse Slagelse
248 University Hospital of Frederiskberg Urhammer Soren Denmark Frederiksberg Frederiksberg
249 Roskilde Hospital Ostergaard Ove Denmark Rosklide Rosklide
250 Regional Hospital Holstebro Oczachowska-Kulik, Anna Ewa Denmark Holstebro Holstebro
251 Aarhus University Hospital, Skejby Povlsen Johan Denmark Aarhus C Aarhus C
252 Steno Diabetes Center Rossing Peter Denmark Gentofte Gentofte
253 Terveystalo Oulu Strand Jorma Finland Oulu Oulu
254 Tampere University Hospital Lahtela Jorma Finland Tampere Tampere
255 Turku University Hospital Kantola Ilkka Finland Turku Turku
256 CHU de Grenoble - Hopital Albert Michallon Zaoui Philippe France Grenoble Grenoble
257 CHU de Nice Esnault Vincent France Nice Nice
258 Clinique du Landy Urena Torres Pablo France Saint Ouen Saint Ouen
259 Hopital de la Conception Dussol Bertrand France Marseille Marseille
260 Hospital European, Georges Pompidou Thervet Eric France Paris Paris
261 Dimokritio University Hospital of Alexandroupoli Passadakis Ploumis Greece Alexandroupolis Alexandroupolis
262 Interbalkan Medical Center Papadimitriou Menelaos Greece Thessaloniki Thessaloniki
263 University General Hospital of Patras Goumenos Dimitrios Greece Patras Patras
264 University General Hospital Liakopoulos Vasilios Greece Thessaloniki Thessaloniki
265 University General Hospital of Ioannina Siamopoulos Konstantinos Greece Ionnina Ionnina
266 SISMANOGLEIO General Hospital of Komotini Mavromatidis Konstantinos Greece Komotini Komotini
267 General Hospital of Athens, Evangelismos Apostolou Theofanis Greece Athens Athens
268 Universitaetsklinikum Aachen Muehlfeld Anja Germany Aachen Aachen
269 Klinische Forschung Berlin GbR Schenkenberger Isabella Germany Berlin Berlin
270 Charite Campus Mitte Budde Klemens Germany Berlin Berlin
271 Universitaetklinikum Dresden Hugo Christian Germany Dresden Dresden
272 Studienzentrum Karlstrasse GmbH Dellanna Frank-Hans Germany Duesseldorf Duesseldorf
273 St. Josefskrankenhaus Hasslacher Christoph Germany Heidelberg Heidelberg
274 Nephrologisches Zentrum Pistrosch Frank Germany Hoyerswerda Hoyerswerda
275 Universitaetsklinikum Jena Wolf Gunter Germany Jena Jena
276 Ludwig Maximiliam Universitaet Muenchen Vielhauer Volker Germany Munich Munich
277 Diabetologische Schwerpunktpraxis Pirna Kosch Christine Germany Pirna Pirna
278 Bieler, Riesa, DE Bieler Tasso Germany Riesa Riesa
279 Diabetologische Schwerpunktpraxis Segiet Thomas Germany Speyer Speyer
280 Robert-Bosch-Krankenhaus Alscher Mark Germany Stuttgart Stuttgart
281 Universitaetsklinikum Wuerzburg Wanner Christoph Germany Wuerzburg Wuerzburg
282 Cork University Hospital Eustace Joesph Ireland Cork Cork
283 St. Vincent's University Hospital O'Shea Donal Ireland Dublin 4 Dublin 4
284 The Adelaide and Meath Hospital Lavin Peter Ireland Dublin 24 Dublin 24
285 Connolly Hospital Sreenan Seamus Ireland Dublin 15 Dublin 15
286 Maccabi Health Services Cohen Josef Israel Rishon Le zion Rishon Le zion
287 Ziv Medical Center Adawi Faiad Israel Safed Safed
288 Ha'Emek Medical Center Mazen Elias Israel Afula Afula
289 Carmel Medical Center Frajewicki Victor Israel Haifa Haifa
290 Barzilai Medical Center Yagil Yoram Israel Ashkelon Ashkelon
291 The Edith Wolfson Medical Center Bar-Dayan Yosefa Israel Holon Holon
292 Meir Medical Center Nacasch Naomi Israel Kfar Saba Kfar Saba
293 IRCCS Fondazione Salvatore Maugeri Esposito Ciro Italy Pavia Pavia
294 Azienda ASST Paga Giovanni XXIII Ruggenenti Piero Italy Bergamo Bergamo
295 Azi Soc Sanitaria Territoriale Rombola Giuseppe Italy Varese Varese
296 Azienda Ospedaliera Sant' Andrea Pugliese Giuseppe Italy Rome Rome
297 Universita della Campania Luig Capasso Giovabattista Italy Naples Naples
298 Ospedale S. Maria della Pieta di Naples Nappi Felice Italy Naples Naples
299 Policlinico Universitario degli Federico II di Naples Russo Domenico Italy Naples Naples
300 Azienda Ospedaliera Bianchi Melacrino Morelli Marino Francesco Italy Reggio Calabria Reggio Calabria
301 Nakadori General Hospital Awasaki Hiroshi Japan Akita-shi Akita-shi
302 National Hospital Organization Asahikawa Medical Center Hirano Fuminori Japan Asahikawa-shi Asahikawa-shi
303 Shimizu Internal Medicine Clinic Taya Noriyasu Japan Asahikawa-shi Asahikawa-shi
304 National Hospital Organization Chiba-East-Hospital Nishimura Motonobu Japan Chiba-shi Chiba-shi
305 Fukuoka University Chikushi Hospital Kobayashi Kunihisa Japan Chikushino-shi Chikushino-shi
306 Kyushu Central Hospital of Mutual Aid Association Goto Daisuke Japan Fukuoka Fukuoka
307 Japanese Red Cross Fukuoka Hospital Sasaki Nobuhiro Japan Fukuoka-shi Fukuoka-shi
308 Funabashi Municipal Medical Center Iwaoka Hideaki Japan Fukuyama-shi Fukuyama-shi
309 Anzai Clinic Anzai Jiichi Japan Hakodate Hakodate
310 Harada Clinic Harada Hiroyuki Japan Hakodate-shi Hakodate-shi
311 Takahashi Hospital, Social Medical Corporation Tsutsui Masahiro Japan Hakodate-shi Hakodate-shi
312 Hamamatsu Medical Center Nagayama Koji Japan Hamamatsu-shi Hamamatsu-shi
313 Higashihiroshima Medical Center Kishimoto Rui Japan Higashihiroshima Higashihiroshima
314 Iwata City Hospital FURUYA Ryuichi Japan Iwata-shi Iwata-shi
315 Rinku General Medical Center KASHINE Susumu Japan Izumisano-shi Izumisano-shi
316 Shimane University Hospital Yamamoto Masahiro Japan Izumo Izumo
317 Tempozan Clinic of Internal Medicine Hashiguchi Yasuhiro Japan Kagoshima Kagoshima
318 Kawanishi City Hospital Ueda Shinichiro Japan Kawanishi-shi Kawanishi-shi
319 St. Marianna University School of Medicine Hospital Shibagaki Yugo Japan Kawasaki-shi Kawasaki-shi
320 Kokura Memorial Hospital Kanai Hidetoshi Japan Kitakyushu Kitakyushu
321 Kobe City Medical Center West Hospital Nakamura Takehiro Japan Kobe-shi Kobe-shi
322 Showa General Hospital Fujita Akira Japan Kodaira-shi Kodaira-shi
323 Itabashi Clinic Itabashi Naoki Japan Koga-shi Koga-shi
324 Koshigaya Municipal Hospital Makita Yuichiro Japan Koshigaya Koshigaya
325 Dokkyo Medical University Koshigaya Hospital Takeda Tetsuro Japan Koshigaya-shi Koshigaya-shi
326 Kumamoto Medical Center ONO Keiko Japan Kumamoto-shi Kumamoto-shi
327 Kawasaki Medical School Hospital Kashihara Naoki Japan Kurashiki-shi Kurashiki-shi
328 St. Mary's Hospital SATO Yuichi Japan Kurume-shi Kurume-shi
329 Rakuwakai Otowa Hosptial YAMAGUCHI Yukinari Japan Kyoto Kyoto
330 Kyoto City Hospital Iehara Noriyuki Japan Kyoto-shi Kyoto-shi
331 Takeda General Hospital Azuma Nobuyuki Japan Kyoto-shi Kyoto-shi
332 Matsue Red Cross Hospital Sato Toshiaki Japan Matsue-shi Matsue-shi
333 Saiseikai Matsuyama Hospital Miyaoka Hiroaki Japan Matsuyama-shi Matsuyama-shi
334 Chita Kosei Hospital Nimura Toshinori Japan Mihama-cho Mihama-cho
335 Miyazaki Prefectural Miyazaki Hospital Ikeda Naoko Japan Miyazaki-shi Miyazaki-shi
336 Ato Internal Medicine Clinic Ato Keita Japan Muroran Muroran
337 Chubu Rosai Hospital Nakashima Eitaro Japan Nagoya-shi Nagoya-shi
338 Meitetsu Hospital Okamoto Hideki Japan Nagoya-shi Nagoya-shi
339 NHO Nagoya Medical Center Yambe Yuko Japan Nagoya-shi Nagoya-shi
340 Nakakinen Clinic Osonoi Takeshi Japan Naka Naka
341 Saiseikai Niigata Daini Hospital Suzuki Katsunori Japan Niigata-shi Niigata-shi
342 Kobari General Clinic Watanabe Shuichi Japan Noda Noda
343 Jiyugaoka Yamada Clinic Yamada Daishiro Japan Obihiro Obihiro
344 Obihiro Dai-ichi Hospital Sakai Takashi Japan Obihiro-shi Obihiro-shi
345 Takagi Hospital Ono Yasuhiro Japan Okawa-shi Okawa-shi
346 Osaka Gyoumeikan Hospital Makino Shinya Japan Osaka Osaka
347 Osaka General Medical Center Umayahara Yutaka Japan Osaka-shi Osaka-shi
348 Otsu Municipal Hospital Isono Motohide Japan Otsu-shi Otsu-shi
349 Ibaraki Seinan Medical Center Hospital Iitsuka Tadashi Japan Sakai-machi Sakai-machi
350 Asama General Hospital Naka Motoji Japan Saku-shi Saku-shi
351 Sanuki Municipal Hospital Inoue Toshihiko Japan Sanuki-shi Sanuki-shi
352 Sapporo Medical Center NTT EC Nagai Sou Japan Sapporo-shi Sapporo-shi
353 Manda Memorial Hospital Tsuchida Kenichi Japan Sapporo-shi Sapporo-shi
354 Suruga Clinic Yamauchi Akira Japan Shizuoka Shizuoka
355 Shunan City Shinnanyo Hospital Matsutani Akira Japan Shunan-shi Shunan-shi
356 Takamatsu Red Cross Hospital ISHIKO Tamayo Japan Takamatsu Takamatsu
357 Takatsuki Red Cross Hospital Kaneko Shizuka Japan Takatsuki-shi Takatsuki-shi
358 Tamana Central Hospital Matsuda Hirofumi Japan Tamana-shi Tamana-shi
359 Tokushima University Hospital Matsuhisa Munehide Japan Tokushima Tokushima
360 Tokyo Kamata Medical Center TAKEMOTO Ikutake Japan Tokyo Tokyo
361 National Center for Global Health and Medicine Hospital TSUJIMOTO Tetsuro Japan Tokyo Tokyo
362 MAKITA General Hospital Kosuge Keiichiro Japan Tokyo Tokyo
363 The Institute for Adult Diseases Onishi Yukiko Japan Tokyo Tokyo
364 Tokyo-Eki Center-Building Clinic Kiyosue Arihiro Japan Tokyo Tokyo
365 JA Toride Medical Center Maeda Yoshitaka Japan Toride-shi Toride-shi
366 Toyota Memorial Hospital Shinoda Junji Japan Toyota-shi Toyota-shi
367 Mie Central Medical Center Tanaka Tsuyoshi Japan Tsu Tsu
368 Fujii Clinic Fujii Shinya Japan Ube Ube
369 National Hospital Organization Shinshu Ueda Medical Center Tanaka Yukio Japan Ueda Ueda
370 Urasoe Sogo Hospital Ishikawa Kazuo Japan Urasoe-shi Urasoe-shi
371 Okamoto Internal Medicine Office Imura Mitsuo Japan Yaizu Yaizu
372 National Hospital Organization Yokohama Medical Center Ujihara Makoto Japan Yokohama-shi Yokohama-shi
373 Tokui Internal Medicine Clinic Tokui Mikiya Japan Yokohama-shi Yokohama-shi
374 Nakajima Naika Clinic MUKASA Koji Japan Yokosuka-shi Yokosuka-shi
375 Korea University Ansan Hospital Kim Nan Hee Korea, Republic Of Ansan Ansan
376 Korea University Ansan Hospital Cha Dae-Ryong Korea, Republic Of Ansan Ansan
377 Soonchunhayng University Bucheon Hospital Mok Ji Oh Korea, Republic Of Bucheon-si Bucheon-si
378 Dong-A University Hospital Suh Sung Korea, Republic Of Busan Busan
379 Inje University Busan Paik Hospital Park Jeong Hyun Korea, Republic Of Busan Busan
380 Chungbuk National University Hospital Oh Tae Keun Korea, Republic Of Cheongju-si Cheongju-si
381 Chuncheon Sacred Heart Hospital Choi Moon-Gi Korea, Republic Of Chuncheon Chuncheon
382 Kyungpook National University Hospital Lee In-Kyu Korea, Republic Of Daegu Daegu
383 Daegu Catholic University Medical Center Shon Ho Sang Korea, Republic Of Daegu Daegu
384 Keimyung University Dongsan Hospital Cho Ho Chan Korea, Republic Of Daegu Daegu
385 Yeungnam University Medical Center Lee Hyoung Woo Korea, Republic Of Daegu Daegu
386 Chungnam National University Hospital Lee Kang-Wook Korea, Republic Of Daejeon Daejeon
387 Myongji Hospital Lee Jae Hyuk Korea, Republic Of Goyang Goyang
388 Hanyang University Guri Hospital Yi, Joo Hark Korea, Republic Of Guri Guri
389 Chosun University Hospital Kim Sang Yong Korea, Republic Of Gwangju Gwangju
390 Wonkwang University School Of Medicine & Hospital Cho, Chung Gu Korea, Republic Of Iksan Iksan
391 Gachon University Gil Hospital Kim Byung-Joon Korea, Republic Of Incheon Incheon
392 Jeju National University Hospital Lee Sang Ah Korea, Republic Of Jeju-si Jeju-si
393 Chonbuk National University Hospital Park Tae-Sun Korea, Republic Of Jeonju Jeonju
394 Pusan National University Hospital Kim In-Joo Korea, Republic Of Pusan Pusan
395 Seoul National University Bundang Hospital Jang Hak-Chul Korea, Republic Of Seongnam Seongnam
396 Bundang Cha Hospital Cho Yong-Wook Korea, Republic Of Seongnam Seongnam
397 Gangnam Severance Hospital Ahn Chul Woo Korea, Republic Of Seoul Seoul
398 Hallym University Kangdong Sacred Heart Hospital Kim Doo-Man Korea, Republic Of Seoul Seoul
399 Samsung Medical Center Lee Moon-Kyu Korea, Republic Of Seoul Seoul
400 Seoul National University Hospital Park Kyong-Soo Korea, Republic Of Seoul Seoul
401 Gangdong Kyunghee University Hospital Ahn Kyu Jeung Korea, Republic Of Seoul Seoul
402 Kyunghee University Medical Center Woo Jeong-Taek Korea, Republic Of Seoul Seoul
403 The Catholic Univ. of Korea Seoul, St. Mary's Hospital Yoon Kun-Ho Korea, Republic Of Seoul Seoul
404 Korea Universtiy Guro Hospital Choi Kyung Korea, Republic Of Seoul Seoul
405 Korea University Anam Hospital Kim Sin-Gon Korea, Republic Of Seoul Seoul
406 The Catholic University of Korea St. Paul's Hospital Kim Byung Soo Korea, Republic Of Seoul Seoul
407 Asan Medical Center Kim Min Seon Korea, Republic Of Seoul Seoul
408 Severance Hospital Kim Beom Seok Korea, Republic Of Seoul Seoul
409 Ajou University Hospital Lee Kwan-Woo Korea, Republic Of Suwon Suwon
410 Uijeongbu St. Mary's Hospital Yoon Sun Ae Korea, Republic Of Uijeongbu Uijeongbu
411 Ulsan University Hospital Nam-Goong II-Seong Korea, Republic Of Ulsan Ulsan
412 Yonsei University Wonju Severance Christian Hospital Chung Choon Hee Korea, Republic Of Wonju Wonju
413 Hospital Selayang Wong Hin Seng Malaysia Batu Caves Batu Caves
414 Hospital Serdang Goh Bak Leong Malaysia Kajang Kajang
415 University Sains Malaysia Mohamed Mafauzy Malaysia Kota Bharu Kota Bharu
416 Hospital Raja Perempuan Zainab II Hassen Wan Hasnul Halimi Malaysia Kota Bharu Kota Bharu
417 Hospital Kuala Lumpur Ahmad Ghazali Malaysia Kuala Lumpur Kuala Lumpur
418 Hospital Universiti Kebangsaan Malaysia Sukor Norlela Malaysia Kuala Lumpur Kuala Lumpur
419 Hospital Tengku Ampuan Afzan Nik Ahmad Nik Malaysia Kuantan Kuantan
420 Hospital Melaka Shalini Vijayasingham Malaysia Melaka Melaka
421 Hospital Pulua Pinang c/o Penang Medical College Aziz Nor Azizah Malaysia Pulau Pinang Pulau Pinang
422 Hospital Putrajaya Hussein Zanariah Malaysia Putrajaya Putrajaya
423 Hospital Tuanku Jafaar Adam Noor Malaysia Seremban Seremban
424 Hospital Taiping Ramanathan GR Malaysia Taiping Taiping
425 Hospital Taiping Vaithilingam Indralingan Malaysia Taiping Taiping
426 Centro de Investigacion Clinica del Pacifico Leguizamo-Dimas Aniceto Mexico Acapulco Acapulco
427 Clinica San Cosme Chew Wong Alfredo Mexico Aguascalientes Aguascalientes
428 Instituto de Diabetes Obesidad y Nutricion S.C. Sauque Reyna Leobardo Mexico Cuernavaca, Morelos Cuernavaca, Morelos
429 Investigacion Nefrologica S.C. Bochicchio-Ricardelli Tomasso Mexico Cuernavaca, Morelos Cuernavaca, Morelos
430 Instituto Jalisciense de Investigacion en Diabetes Obesidad Gonzalez-Galvez Guillermo Mexico Guadalajara Guadalajara
431 Area Medica SANEFRO Renoirte Lopez Karina Mexico Guadalajara Guadalajara
432 Instituto Nacioanl de Ciencias Medicas Nutricion S. Zubiran Nino, Jose Antonio Mexico Mexico City Mexico City
433 Instituto Nacional de Cardiologia Madero Rovalo Magdalena Mexico Mexico City Mexico City
434 Hospital Universitario Dr. Jose Eleuterio Gonzalez Gonzalez Gonzalez Jose Mexico Monterrey, N.L. Monterrey, N.L.
435 Hospital y Clinica OCA Rico Hernandez Raul Mexico Monterrey, Nuevo Leon Monterrey, Nuevo Leon
436 Unidad de Prevencion y Atencion Cardiometabolica (UPAC) Carranza-Madrigal Jaime Mexico Morelia, Michoacan Morelia, Michoacan
437 Hospital Central Dr. Ignacio Morones Prieto Chevaile-Ramos Jose Mexico San Luis Potosi San Luis Potosi
438 Universitair Medisch Centrum Groningen Gansevoort Ron Netherlands Groningn Groningn
439 Albert Schweitzer Ziekenhuis Smak Gregoor Peter Netherlands Dordrecht Dordrecht
440 Ziekenhuis Groep Twente Laverman Gozewijn Netherlands Almelo Almelo
441 Gelre Hospital Apeldoorn Barendregt JNM (Jos) Netherlands Apeldoorn Apeldoorn
442 Meander Medisch Centrum Luik Peter Netherlands Amersfoort Amersfoort
443 Auckland City Hospital Pilmore Helen New Zealand Auckland Auckland
444 Dunedin Hospital Schollum John New Zealand Dunedin Dunedin
445 Waikato Hospital Rabindranath Kannaiyan New Zealand Hamilton Hamilton
446 Taranaki Base Hospital Hayat Ashik New Zealand New Plymouth New Plymouth
447 North Shore Hospital Miller Steven New Zealand Takapuna Takapuna
448 Instituto Endocronolocigo Farfan E.I.R.L Farfan-Aspilcueta Julio Peru Arequipa Arequipa
449 Exacta Lab SAC Burga Nunez Jose Peru Arequipa Arequipa
450 Instituto Delgado de Investigacion Medica Delgado-Butron Cesar Peru Arequipa Arequipa
451 Hospital Nacional Alberto Sabogal Sologuren Herrada Orue Benjamin Peru Callao Callao
452 Hospital Nacional Adolfo Guevara Velasco Essalud Zea-Nunez Carlos Antonio Peru Cusco Cusco
453 Centro de Investigacion y Atencion Cardiovascular SAC. Calderon Ticona Jorge Peru Lima Lima
454 Clinica de Diabetes S.A.C. Zapata-Rincon Luis Peru Lima Lima
455 Centro Medico Clinica San Judas Tadeo Dextre Espinoza Augusto Peru Lima Lima
456 Hospital Nacional Arzobispo Loayza Medina-Santander Boris Peru Lima Lima
457 Clinica Virgen Maria Auxiliadora Vargas-Gonzales Rolando Peru Piura Piura
458 NZOZ Specjalistyczny Osrodek Arciszewska Malgorzata Poland Bialystok Bialystok
459 NZOZ Diab Serwis S.C. Popenda Grazyna Poland Chorzow Chorzow
460 NZOZ SALVIA Madej Andrzej Poland Katowice Katowice
461 Krakowskie Centrum Medyczne Sp. z o.o. Kowalczyk-Michalek Martyna Poland Krakow Krakow
462 NZOZ Centrum Medyczne ProMiMed Sp. z o.o., sp.k Necki Miroslaw Poland Krakow Krakow
463 SPZOZ Uniwersytecki Szpital Kliniczny nr 1 Nowicki Michal Poland Lodz Lodz
464 NZOZ Przychodnia Specjalistyczna MEDICA Skokowska Ewa Poland Lublin Lublin
465 Centrum Medyczne Medyk Mazur Stanislaw Poland Rzeszow Rzeszow
466 Samodzielny Publiczny Szpital Kliniczny Nr 2 PUM w Szczecini Ciechanowski Kazimierz Poland Szczecin Szczecin
467 Centrum Uslug Medycznych Dializa Wruk Michal Poland Szczecinek Szczecinek
468 Medica pro Familia Sp. z o.o. S.K.A Klodawska Katarzyna Poland Warsaw Warsaw
469 Hospital Curry Cabral,PT Ferreira Annibal Portugal Lisbon Lisbon
470 Associacao Protectora dos Diabeticos de Portugal Brine Rita Portugal Lisbon Lisbon
471 Centro Hospitalar do Porto Cabrita Antonio Portugal Porto Porto
472 Health Preventive Services Comulada-Rivera Angel Puerto Rico Bayamon Bayamon
473 Instituto Renal del Este Galindo Ramos Eugenia Puerto Rico Caguas Caguas
474 Caparra Internal Medicine Matta Fontanet Evelyn Puerto Rico Rio Grande Rio Grande
475 University of Puerto Rico Burgos-Calderon Rafael Puerto Rico Rio Piedras Rio Piedras
476 PR Renal Health and Research INC. Calderon-Ortiz, Ricardo Puerto Rico Toa Baja Toa Baja
477 O.D. Medica SRL Tivadar Simona Romania Bucharest Bucharest
478 Centrul Medical Unirea SRL Hancu Nicolae Romania Cluj-Napoca Cluj-Napoca
479 Spitalul Clinic Judetean de Urgenta Cluj-Napoca Duma Livia Romania Cluj-Napoca Cluj-Napoca
480 Spitalul Clinic Judetean de Urgenta Constanta Tuta Liliana Romania Constanta Constanta
481 Milena Sante SRL Mistodie Cristina Romania Galati Galati
482 Consultmed SRL Pintilei Ella Romania Iasi Iasi
483 Municipal Clinical Hospital Bako Gabriel Romania Oradea Oradea
484 Spitalul Judetean de Urgenta Pitesti Tutescu Adriana Romania Pitesti Pitesti
485 SC Centrul Medical Munteanu Mircea Romania Timisoara Timisoara
486 Sptalul Clinic Judetean de Urgenta Timisoara Petrica Ligia Romania Timisoara Timisoara
487 Sptalul Clinic Judetean de Urgenta Timisoara Timar Romulus Romania Timisoara Timisoara
488 City Hospital No 6 Kuzin Anatoly Russian Federation Chelyabinsk Chelyabinsk
489 Gatchina Central District Clinical Hospital Yavdosyuk Andrey Russian Federation Gatchina Gatchina
490 Irkutsk State Medical Academy of Postgraduate Education Bardymova Tatiana Russian Federation Irkutsk Irkutsk
491 Kazan State Medical University Sigitova Olga Russian Federation Republic of Tatarstan Kazan
492 Kazan State Medical University Maksudova Adelya Russian Federation Republic of Tatarstan Kazan
493 Kirov City Clinical Hospital 1 Solovev Oleg Russian Federation Kirov Kirov
494 Krasnoyarsk Interdistrict Clinical Emergency Care Hospital Rechkova Elena Russian Federation Krasnoyarsk Krasnoyarsk
495 Endocrinology Research Center Shamkhalova Minara Russian Federation Moscow Moscow
496 Moscow - Out-patient Clinic #3 Pikalova Natalia Russian Federation Moscow Moscow
497 City Hosp 33 of Leninskiy District of City Nizhniy Novgorod Pichkov Dmitry Russian Federation Nizhniy Novgorod Nizhniy Novgorod
498 Scientific Instituti of Clinical and Experimental Lymphology Klimontov Vadim Russian Federation Novosibirsk Novosibirsk
499 Orenburg State Medical Academy Sayfutdinov Rustam Russian Federation Orenburg Orenburg
500 Perm Regional Hospital for War Veterans Koziolova Natalya Russian Federation Perm Perm
501 Republican Hospital named after V. A. Baranov Barysheva Olga Russian Federation Petrozavodsk Petrozavodsk
502 City Out-patient Clinic #17 Lantseva Olga Russian Federation Saint-Petersburg Saint-Petersburg
503 City Clinical Hospital # 38 named after N.A. Semashko Zrazhevskiy Konstantin Russian Federation Saint-Petersburg Saint-Petersburg
504 St. Petersburg Medical Univ na I.P. Pavlov Karonova Tatiana Russian Federation Saint-Petersburg Saint-Petersburg
505 City Clinical Hospital # 31 Essaian Ashot Russian Federation Saint-Petersburg Saint-Petersburg
506 GBOU VPO Saratov State Medical University Shvarts Yuri Russian Federation Saratov Saratov
507 Smolensk State Medical Academy Reshedko Galina Russian Federation Smolensk Smolensk
508 Federal State Institution Sardinov Ruslan Russian Federation Republic of Tatarstan St. Petersburg
509 Siberian State Medical University Samoylova Yulia Russian Federation Tomsk Tomsk
510 Research Institute for Cardiology Mordovin Viktor Russian Federation Tomsk Tomsk
511 Regional Clinical Hospital of Yaroslavl Region Marasaev Vyacheslav Russian Federation Republic of Tatarstan Yaroslavl
512 Tan Tock Seng Hospital Liew Adrian Singapore Singapore Singapore
513 Khoo Teck Puat Hospital Yeoh Lee Ying Singapore Singapore Singapore
514 National University Hospital Teo, Boon Wee Singapore Singapore Singapore
515 Metabolic Center of Dr K.Raslova, ltd Raslova Katarina Slovakia Bratislava Bratislava
516 Medispektrum, sro Ilavska Adriana Slovakia Bratislava Bratislava
517 FMC Dialysis Services Fekete Jozef Slovakia Bratislava Bratislava
518 Slovenska Zdravotnica Univerzita Oksa Adrian Slovakia Bratislava Bratislava
519 ProVitae-Medical Centre Zachar Andrej Slovakia Bratislava Bratislava
520 FMC-dialyzacne sluzby, spol.s r.o Obetkova Ida Slovakia Hlohovec Hlohovec
521 Medikol s.r.o. Kolesarova Eva Slovakia Kosice Kosice
522 AGTO spol. s.r.o. Tkac Ivan Slovakia Kosice Kosice
523 FMC Dialyzacne sluzby s.r.o. Rosenberger Jaroslav Slovakia Kosice Kosice
524 SMOLKO s.r.o. Smolko Peter Slovakia Kosice Kosice
525 Interna SK s.r.o. Fulopova Alla Slovakia Svidnik Svidnik
526 Groote Schuur Hospital Okpechi Ikechi South Africa Western Cape Cape Town
527 Langeberg Clinical Trials Trokis Julien South Africa Western Cape Cape Town
528 Dr P J Sebastian Sebastian Peter South Africa KwaZulu-Natal Durban
529 Newkwa Medical Centre Ramlachan Padaruth South Africa KwaZulu-Natal Durban
530 St. Augustine's Hospital Naiker Puvanesveri South Africa KwaZulu-Natal Durban
531 Centre for Diabetes and Endocrinology Distiller Lawrence South Africa Gauteng Johannesburg
532 Makan, Lenasia, SA Makan Hemant South Africa Lenasia Lenasia
533 Paarl Research Centre Coetzee Kathleen South Africa Western Cape Paarl
534 Soweto Clinical Trial Centre Bhorat Asad South Africa Soweto Soweto
535 Clinical Projects Research van Zyl Louis South Africa Western Cape Worcester
536 Complejo Hospitalario Universitario de A Coruna Soto Gonzalez Alfonso Spain A Coruna A Coruna
537 Hospital Universitario Germans Trias i Pujol Bonet Jose Spain Badalona - Barcelona Badalona - Barcelona
538 Hospital Parc de Salut del Mar Pascual Santos Julio Spain Barcelona Barcelona
539 Hospital Universitario Bellvitge Grinyo Josep Spain Barcelona Barcelona
540 Hospital Universitario Vall d'Hebron Seron Daniel Spain Barcelona Barcelona
541 Fundacion Puigvert Calero Gonzalez Francesca Spain Barcelona Barcelona
542 Hospital Universitario de Basurto Arrieta Lezarna Javier Spain Bilbao Bilbao
543 Hospital da Costa Cigarran Guldris Secundino Spain Burela Burela
544 Hospital Universitario Reina Sofia Santamaria Olmo Rafael Spain Cordoba Cordoba
545 Hospital Universitario de Gran Canarias Dr. Negrin Rodriguez-Perez Jose Spain Las Palmas Las Palmas
546 Hospital Universitario Arnau de Vilanova Fernandez Giraldez Elvira Spain Lleida Lleida
547 Hospital Universitario Fundacion Alcorcon Fernandez Juarez Gema Spain Madrid Madrid
548 Fundacion Jimenez Diaz Egido Jesus Spain Madrid Madrid
549 Hospital Clinico San Carlos Herrero Calvo Jose Spain Madrid Madrid
550 Hospital Universitario 12 de Octubre Praga Terente Manuel Spain Madrid Madrid
551 Hospital Universitarrio Puerta de Hierro Majadahonda Marques Vidas Maria Spain Madrid Madrid
552 Hospital Universitario Virgen de la Victoria Valera Cortes Ildefonso Spain Malaga Malaga
553 Hospital Universitario Marques de Valdecilla Fernandez Fresnedo Gema Spain Santander (Cantabria) Santander (Cantabria)
554 Hospital Universitario Nuestra Senora de Candelaria Navarro Gonzalez Juan Spain Tenerife Tenerife
555 Hospital General Univ de Valencia Galan Antonio Spain Valencia Valencia
556 Hospital Universitario Dr. Peset Gorriz Jose Spain Valencia Valencia
557 Hospital Universitari i Politecnin la Fe Hernandez-Jaras Julio Spain Valencia Valencia
558 Hospital de Txagorritxu Minguela Pesquera Jose Ignacio Spain Vitoria Vitoria
559 Orebro Universitetssjukhus Hellberg Olof Sweden Orebro Orebro
560 Uppsala University Hospital Fellstrom Bengt Sweden Uppsala Uppsala
561 Hualien Tzu Chi Hospital Wu Du-An China Taiwan Hualien
562 Far Eastern Memorial Hospital Jiang Ju-Ying China Taiwan New Taipei
563 Cardinal Tien Hospital Dee Pei China Taiwan New Taipei
564 China Medical University Hospital Chen Ching-Chu China Taiwan Taichung
565 Taichung Veterans General Hospital Sheu Wayne China Taiwan Taichung
566 Chung Shan Medical University Huang Chien-Ning China Taiwan Taichung
567 Kuang Tien General Hospital Tseng Shih-Ting China Taiwan Taichung
568 Taichung Hospital Sheen Yi-Jing China Taiwan Taichung
569 Chi-Mei Medical Center Tien Kai-Jen China Taiwan Tainan
570 Cathay General Hospital Lin Ching-Ling China Taiwan Taipei
571 Taipei Medical University Hospital Wu Mai-Szu China Taiwan Taipei
572 MacKay Memorial Hospital Chien Ming-Nan China Taiwan Taipei
573 Baskent University School of Medicine Sezer Siren Turkey Ankara Ankara
574 Akdeniz University School of Medicine Sari Ramazan Turkey Ankara Ankara
575 Adnan Menderes University Yenicerioglu Yavuz Turkey Aydin Aydin
576 Istanbul University Medical Faculty Satman Ilhan Turkey Istanbul Istanbul
577 Istanbul University Medical Faculty Yildiz Alaattin Turkey Istanbul Istanbul
578 Kocaeli University Medical Faculty Kalender Gonullu Betul Turkey Kocaeli Kocaeli
579 Chernivtsi Regional Clinical Hospital Zub Lilia Ukraine Chernivtsi Chernivtsi
580 Ukrainian State Institution of Medical and Social Problems Panina Svitlana Ukraine Dnipropetrovsk Dnipropetrovsk
581 Ivano-Frankivsk Regional Clinical Hospital Legun Oleg Ukraine Ivano-Frankivsk Ivano-Frankivsk
582 Kharkiv City Clinical Emergency Hospital Bilchenko Oleksandr Ukraine Kharkiv Kharkiv
583 Kharkov City Clinical Hospital #27 Zolotaikina Viktoriia Ukraine Kharkiv Kharkiv
584 SI Institute of Therapy AMS of Ukraine n.a. Mala L.T. Topchii Ivan Ukraine Kharkiv Kharkiv
585 VP Komissarenko National Academy of Medical Sciences Korpachev Vadym Ukraine Kiev Kiev
586 Kiev Regional Clinical Hospital Shen Andriy Ukraine Kyiv Kyiv
587 Polyclinic of Administration of Medical Services Mankovskyy Borys Ukraine Kyiv Kyiv
588 Communal Institution Odesa Regional Clinical Hospital Petrosyan Olena Ukraine Odesa Odesa
589 Transcarpathian Regional Clin. Hos. Named after Andriy Novak Stryzhak Vasyl Ukraine Uzhgorod Uzhgorod
590 Clinic of Scientific Research Institute for Hadicapped Shevchuk Sergii Ukraine Vinnytsya Vinnytsya
591 Vinnytsya National Medical University n.a. M.I. Pyrogov Stanislavchuk Mykola Ukraine Vinnytsya Vinnytsya
592 Regional Clinical Hospital of Zhytomyr Kuskalo Petro Ukraine Zhytomyr Zhytomyr
593 Belfast City Hospital Maxwell Peter United Kingdom Belfast Belfast
594 Ninewells Hospital Brennan Geraldine United Kingdom Dundee Dundee
595 South Glasgow Universita Hospi Mark Patrick United Kingdom Glasgow Glasgow
596 Kings College Hospital Kon, Sui Phin United Kingdom London London
597 Guy's Hospital Gnudi Luigi United Kingdom London London
598 The Royal Free Hospital Patel Dipesh United Kingdom London London
599 North Middlesex Hospital NHS Trust Tindall Hilary United Kingdom London London
600 Salford Royal NHS Foundation Trust Kalra Phillip United Kingdom Salford Salford
601 Queen Mary Hospital Sydney Tang 中国 Hong Kong Hong Kong
602 Prince of Wales Hospital Risa Ozaki 中国 Hong Kong Hong Kong
603 Queen Mary Hospital Kathryn Tan 中国 Hong Kong Hong Kong
604 河北医科大学第二医院 傅淑霞 中国 河北省 石家庄
605 宁波市第二医院 罗群 中国 浙江省 宁波
606 郑州大学第一附属医院 刘章锁 中国 河南省 郑州
五、伦理委员会信息
序号 名称 审查结论 批准日期/备案日期
1 南方医科大学南方医院医学伦理委员会 同意 2014-10-23
六、试验状态信息
1、试验状态
主动暂停
2、试验人数
目标入组人数 国内: 280 ; 国际: 4148 ;
已入组人数 国内: 登记人暂未填写该信息; 国际: 登记人暂未填写该信息;
实际入组总人数 国内: 203  ; 国际: 3668 ;
3、受试者招募及试验完成日期
第一例受试者签署知情同意书日期 国内:2015-02-02;     国际:2013-06-12;
第一例受试者入组日期 国内:登记人暂未填写该信息;     国际:登记人暂未填写该信息;
试验完成日期 国内:2017-11-10;     国际:2017-11-10;
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